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As with any disease that strikes so many, there are ample resources seeking to educate the general public to its extent and nature. Some resources our firm has found helpful in understanding both breast cancer and the casual link between it and in utero DES exposure are:

  • Palmer J, Wise L, Hatch E, et al. Prenatal diethylstilbestrol exposure and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2006;15(8):1509-1514.
  • Munoz-de-Toro M, Markey C, Wadia P, et al. Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice. Endocrinology 2005;146(9):4138-4147.
  • Rothschild T, Boylan E, Calhoon R, Vonderhaar B. Transplacental effects of diethylstilbestrol on mammary development and tumorigenesis in female ACI rats. Cancer Research 1987;47:4508-4516.
  • Potischman N, Troisi R, Thadhani R, et al. Pregnancy hormone concentrations across ethnic groups: implications for later cancer risk. Cancer Epidemiol Biomarkers Prev 2005;14(6):1514-1520.
  • Lagiou P. Intrauterine exposures, pregnancy estrogens and breast cancer risk: where do we currently stand? Breast Cancer Research 2006;8:112 (doi:10.1186/bcr1615).
  • Kitajewski J and Sassoon D. The emergence of molecular gynecology: homeobox and Wnt genes in the female reproductive tract. BioEssays 2000;22:902-910.
  • Hovey R, Asai-Sato M, Warri A, et al. Effects of neonatal exposure to diethylstilbestrol, tamoxifen, and toremifene on the BALB/c mouse mammary gland. Biology of Reproduction 2005;72:423-435.
  • Mori T, Bern H, Mills K, and Young P. Long-term effects of neonatal steroid exposure on mammary gland development and tumorigenesis in mice. J Natl Cancer Inst 1976;57(5):1057-1061.
  • Kaufman R, Adam E, Hatch E, et al. Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring. Obstetrics & Gynecology 2000;96(4):483-489.
  • Pharoah P, Antoniou A, Easton D, and Ponder B. Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 2008;358:2796-2803.
  • Park S.K., Kang D, McGlynn K, et al. Intrauterine environments and breast cancer risk: meta-analysis and systematic review. Breast Cancer Research 2008;10:R8 (doi: 10.1186/bcr1850).
  • Keri R, Ho S, Hunt P, Knudsen K, Soto A, and Prins G. An evaluation of evidence for the carcinogenic activity of bisphenol A. Reproductive Toxicology 2007;24:240-252.
  • Narbaitz R, Stumpf W.E., and Sar M. Estrogen receptors in mammary gland primordial of fetal mouse. Anat. Embryol. 1980;158:161-166.
  • Howard B and Gusterson B. Human breast development. Journal of Mammary Gland Biology and Neoplasia 2000;Vol. 5, No. 2:119-137.
  • Richert M, Schwertfeger K, Ryder J, and Anderson S. An atlas of mouse mammary gland development. Journal of Mammary Gland Biology and Neoplasia 2000;Vol. 5, No. 2:227-241.
  • Vandenberg L, Maffini M, et al. Exposure to environmentally relevant doses of the xenoestrogen Bisphenol-A alters development of the fetal mouse mammary gland. Endocrinology 2007;148(1):116-127.
  • Elk, Ronit and Monica Morrow. Breast Cancer for Dummies. Indianapolis: Wiley Publishing Inc., 2003.
  • Chan, David. Breast Cancer - Real Questions, Real Answers. New York: Marlowe & Company, 2006.
  • Hatch E.E. et al. Age at natural Menopause in Women Exposed to Diethylstilbestrol in Utero. Am. J. Epidemiol. 164:682-688, 2006.
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